Bear in mind dual core is *quite* old now - core 2 are more modern and 64 bit. The system config does depend on what OS you want to run and what you want to do with it - for games you need much more performance (and excellent video card) than for simply surfing the web. I would suggest a HD of size 160 GB plus, a few GB RAM and anything else depends on the system usage.
For mice and keyboards - I use a £9 infrared mouse which is excellent and a 12 year old Acorn keyboard (which is again excellent.) I dont think for mice or keyboards you need to spend a huge amount, just something cheap and cheerful!
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